P42336

PI3 Kinase p110α plays a crucial role in cellular functions such as growth, proliferation, and survival, making the study of PI 3-kinase components vital for understanding various diseases, including cancer. PI3 Kinase p110α is particularly important as PI 3-kinase p110α is frequently mutated in several types of cancer, leading to aberrant signaling and uncontrolled cell growth. Understanding PI3 Kinase p110α interactions with PI3 kinase regulatory subunit p85 is essential, as p85 serves as an adapter that links PI3 Kinase p110α to activated protein tyrosine kinases, thereby facilitating the activation of downstream signaling pathways. PI3 Kinase p110α ability to interact with both p85α and p85β highlights PI3 Kinase p110α versatility and importance in the PI3 kinase signaling cascade, which is critical for maintaining cellular homeostasis and responding to extracellular signals.