P10451

Osteopontin also known as OPN, SPP1, is involved in the attachment of osteoclasts to the mineralized bone matrix. Osteopontin plays a crucial role in various biological processes. Post-translational modifications of OPN, such as phosphorylation and glycosylation, significantly influence molecular weight and functional properties, enabling interactions with specific receptors and proteins to modulate cell adhesion, migration, and immune responses. OPN monoclonal antibody (AKm2A1) helps researchers study this protein, which is predominantly produced by osteoblasts and synthesized in brain and kidneys, demonstrating importance in both skeletal and non-skeletal tissues.