Polyclonal Antibodies - Notch2 Rabbit Polyclonal Antibody

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Notch2 Rabbit Polyclonal Antibody

Catalog #：EAB14160

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB14160-100UL	In Stock	100ul	€258.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	OlaSciences	Phone：+33 (0) 9 77 4001 556
	87, rue des Suisses 65000 Nanterre,	E-mail：ola@olasciences.com
France	France	Web：www.olasciences.com

Product Information
Applications	WB, IHC-P
Species Reactivity	Human, Mouse
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300
MW (kDa)	265
Conjugate	Unconjugate
Specificity	Notch2 Rabbit Polyclonal Antibody detects endogenous levels of Notch2 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Notch receptor 2; hN2; AGS2; HJCYS; NOTCH2
Gene Aliases	NOTCH2
UniProt ID	Q04721
Entrez Gene ID	4853

Product Description

Notch2 is a member of the Notch family. Notch 2 is a crucial component of the Notch signaling pathway, which is integral to cell communication and plays a significant role in regulating cell fate decisions during development. Notch 2 is primarily located in the cell membrane, where this receptor interacts with ligands such as Jagged and Delta, facilitating essential processes like cell differentiation and tissue development. Proper functioning of Notch 2 is vital, as dysregulation can lead to various developmental disorders and has been implicated in cancer progression. Notch 2′s interaction with ligands not only influences cell fate but also contributes to stem cell population maintenance and immune response regulation.

Product Image Gallery
Western blot analysis of extracts on Hela, 293T cells, using Notch2 Rabbit Polyclonal Antibody (EAB14160) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Predicted band size: 265 kDa; Observed band size: 120, 280 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol