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NKX2-5 Rabbit Polyclonal Antibody
Catalog #:EAB14304
  SKU-Pack Size Availability Size Price
EAB14304-100UL In Stock 100ul £218.90
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CUlabSciences Phone:+44 (0) 1232 330008
Cambridge House St Thomas' Place Ely, E-mail:sales@culabsciences.co.uk
United Kingdom Cambridge CB27 9RD UK Web:www.culabsciences.co.uk
Product Information
Applications WB, IF/ICC
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit IgG
Clonality Polyclonal
Applications Dilutions WB=1:500-2000 
IF/ICC=1:50-300 
MW (kDa) 35
Conjugate Unconjugate
Specificity NKX2-5 Rabbit Polyclonal Antibody detects endogenous levels of NKX2-5 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) NK2 homeobox 5; CSX; CSX1; VSD3; CHNG5; HLHS2; NKX2E; NKX2.5; NKX4-1; NKX2-5
Gene Aliases NKX2-5
UniProt ID

P52952

Entrez Gene ID

1482

Product Description

NKX2-5 also known as Csx, NKX-2.5 is a homeobox-containing transcription factor. NKX2-5 plays a crucial role in cardiac development as a transcription factor that regulates the expression of genes essential for heart formation and function. NKX2-5 is primarily located in the nucleus, where DNA binding influences the transcription of target genes involved in cardiomyocyte differentiation and cardiac morphogenesis. Proper localization of NKX2-5 ensures appropriate gene activation during embryonic development, particularly during critical stages of heart formation. Disruptions in NKX2-5 expression or function can lead to severe developmental issues, including congenital heart defects and cardiovascular anomalies.

Product Image Gallery
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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