SKU-Pack Size | Availability | Size | Price | |
EAB22584-100UL | In Stock | 100ul | $343.50 |
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EbioCell | Phone:(540) 808-3925 |
Imperial Business Park 4819 Emperor Boulevard, | E-mail:order@ebiocell.com | |
United States | Suite 408 Durham, NC 27703, USA | Web:www.ebiocell.com |
Product Information | |
Applications | WB |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit IgG |
Clonality | Monoclonal |
Applications Dilutions | WB=1:500-2000 |
MW (kDa) | 149 |
Conjugate | Unconjugate |
Specificity | NEDD4 Rabbit Monoclonal Antibody detects endogenous levels of NEDD4 protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | NEDD4-1; NEDD4; RPF1; E3 ubiquitin-protein ligase NEDD4; Receptor-potentiating factor 1; mKIAA0093; NEDD-4; Nedd4a; PIG53; RPF-1 |
Gene Aliases | NEDD4 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. |
Product Image Gallery | |
![]() Western blot analysis of extracts on different cells, using NEDD4 Rabbit Monoclonal Antibody (EAB22584) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Lane1: A549 Lane2: NIH/3T3 |
Specific Protocols | |