Polyclonal Antibodies - MCM7 Rabbit Polyclonal Antibody

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MCM7 Rabbit Polyclonal Antibody

Catalog #：EAB14257

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB14257-30UL	In Stock	30ul	￡97.90
EAB14257-100UL	In Stock	100ul	￡218.90
EAB14257-200UL	In Stock	200ul	￡372.90

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, IHC-P, IF, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300 IF=1:50-300
MW (kDa)	81
Conjugate	Unconjugate
Specificity	MCM7 Rabbit Polyclonal Antibody detects endogenous levels of MCM7 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Minichromosome maintenance complex component 7; MCM2; CDC47; P85MCM; P1CDC47; PNAS146; PPP1R104; P1.1-MCM3; MCM7
Gene Aliases	MCM7
UniProt ID	P33993
Entrez Gene ID	4176

Product Description

MCM7 is a member of the mini-chromosome maintenance (MCM) protein family, MCM7 plays a crucial role in the regulation of DNA replication, ensuring that DNA is replicated only once per cell cycle. This is vital for maintaining genomic stability and preventing over-replication, which can lead to genomic instability and cancer. MCM7, along with other MCM proteins, contains an ATP-binding motif that facilitates the opening of double-stranded DNA in an ATP-dependent manner, a key step in the initiation of DNA replication. MCM7 expression peaks during the transition from the G1 to S phase of the cell cycle and is influenced by E2F transcription factors and various protein kinases. MCM7 interacts with other MCM proteins to form a complex that exhibits DNA helicase activity, essential for unwinding DNA strands during replication.

Product Image Gallery
Western blot analysis of extracts on Hela, HEK293 cells, using MCM7 Rabbit Polyclonal Antibody (EAB14257) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Immunohistochemical analysis of paraffin-embedded Human lung tissue, using MCM7 Rabbit Polyclonal Antibody (EAB14257) at 1:100 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol