SKU-Pack Size | Availability | Size | Price | |
EAB14225-30UL | In Stock | 30ul | €115.70 | |
EAB14225-100UL | In Stock | 100ul | €258.70 | |
EAB14225-200UL | In Stock | 200ul | €440.70 |
Please select the country you are in to find your local distributor. |
SBT BioChem Srl | Phone£º+39 05 7156 8147 | |
Via Ponte di Bagnolo, 811 Bologna, | E-mail£ºinfo@sbtbiochem.it | |
Italy | Italy | Web£ºwww.sbtbiochem.it |
Product Information | |
Applications | WB, ELISA |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000 |
MW (kDa) | 116 |
Conjugate | Unconjugate |
Specificity | KL/Klotho Rabbit Polyclonal Antibody detects endogenous levels of KL/Klotho protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | Klotho; KLA; HFTC3; KL |
Gene Aliases | KL |
UniProt ID | |
Entrez Gene ID |
Product Description | |
Klotho also known as KL, HFTC3 is a type-I membrane protein that is related to beta-glucosidases. The amino terminal extracellular domain has two internal repeats, known as KL-1 and KL-2, which have partial sequence homology to beta-glucosidases and lactase glycosylceramidase, suggesting a role for Klotho in sphingolipid metabolism. The human klotho gene maps to chromosome 13q12 and encodes a 1012 amino acid protein that is abundant in the kidney and brain. Chronic renal failure (CRF) patients express lower levels of klotho mRNA and protein in the kidneys. |
Product Image Gallery | |
Western blot analysis of extracts on Mouse kidney, Mouse brain cells, using KL/Klotho Rabbit Polyclonal Antibody (EAB14225) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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Specific Protocols | |