Polyclonal Antibodies - TIA1 Rabbit Polyclonal Antibody

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TIA1 Rabbit Polyclonal Antibody

Catalog #：EAB22244

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22244-100UL	In Stock	100ul	￡218.90

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email us at info@ebiocell.com

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, IHC-P, IF/ICC
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300 IF/ICC=1:50-300
MW (kDa)	43
Conjugate	Unconjugate
Specificity	TIA1 Rabbit Polyclonal Antibody detects endogenous levels of TIA1 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	TIA1 cytotoxic granule associated RNA binding protein; WDM; ALS26; TIA-1; TIA1
Gene Aliases	TIA1
UniProt ID	P31483
Entrez Gene ID	7072

Product Description

TIA1 is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for this gene.

Product Image Gallery

Western blot analysis of extracts on BT474 cells, using TIA1 Rabbit Polyclonal Antibody (EAB22244) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Predicted band size: 42 kDa; Observed band size: 54 kDa

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue, using TIA1 Rabbit Polyclonal Antibody (EAB22244) at 1:100 dilution.

Immunofluorescence analysis of Hela cell, using TIA1 Rabbit Polyclonal Antibody (EAB22244)(green) at 1:100 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol