SKU-Pack Size | Availability | Size | Price | |
EAB14045-30UL | In Stock | 30ul | £119.90 | |
EAB14045-100UL | In Stock | 100ul | £251.90 | |
EAB14045-200UL | In Stock | 200ul | £405.90 |
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CUlabSciences | Phone:+44 (0) 1232 330008 |
Cambridge House St Thomas' Place Ely, | E-mail:sales@culabsciences.co.uk | |
United Kingdom | Cambridge CB27 9RD UK | Web:www.culabsciences.co.uk |
Product Information | |
Applications | WB, ELISA |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000 |
MW (kDa) | 53 |
Conjugate | Unconjugate |
Specificity | Phospho-TRβ1 (Ser142) Rabbit Polyclonal Antibody detects endogenous levels of TRβ1 protein only when phosphorylated at Ser142. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | THRB; ERBA2; NR1A2; THR1; Thyroid hormone receptor beta |
Gene Aliases | THRB |
UniProt ID | |
Entrez Gene ID |
Product Description | |
TRβ1 (also designated TR beta 1, THRB, THB) is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. |
Product Image Gallery | |
![]() Western blot analysis of extracts on 293 cells treated with PMA, using Phospho-TRβ1 (Ser142) Rabbit Polyclonal Antibody (EAB14045) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
Predicted band size: 53 kDa; Observed band size: 45 kDa |
Specific Protocols | |