Polyclonal Antibodies - TGF-β3 Rabbit Polyclonal Antibody

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TGF-β3 Rabbit Polyclonal Antibody

Catalog #：EAB14036

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB14036-30UL	In Stock	30ul	€115.70
EAB14036-100UL	In Stock	100ul	€258.70
EAB14036-200UL	In Stock	200ul	€440.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

Please select the country you are in to find your local distributor.

	Cambiotech	Phone：+44 (0) 188 448801
	Lanwades Business Park,	E-mail：info@cambiotech.com
Ireland	Kobenhavn K, Ireland	Web：www.cambiotech.com

Product Information
Applications	WB, IHC-P, IF, ELISA
Species Reactivity	Human, Mouse, Rat, Monkey
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300 IF=1:50-300
MW (kDa)	47
Conjugate	Unconjugate
Specificity	TGF-β3 Rabbit Polyclonal Antibody detects endogenous levels of TGF-β3 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	TGFB3; Transforming growth factor beta-3; TGF-beta-3
Gene Aliases	TGFB3
UniProt ID	P10600
Entrez Gene ID	7043

Product Description

TGF-β3 also known as TGF beta3, TGFB3 is essential for proper embryonic development and tissue homeostasis, mediating intercellular signaling that influences cell fate decisions during development. TGFβ3 is synthesized as a precursor protein, cleaved to produce a 112 amino acid polypeptide, which remains associated with a latent portion of the molecule, highlighting complex regulation and function. TGFβ3 expression levels are significant in various pathological conditions, showing overexpression in extramammary Paget′s disease and downregulation in Bowen′s disease, making TGFβ3 a valuable biomarker for tumor activity. TGFβ3 levels correlate strongly with insulin-like growth factor 1 and osteocalcin levels in serum, suggesting involvement in bone metabolism and potential implications in bone-related diseases.

Product Image Gallery
Western blot analysis of extracts on COS7 cells, using TGF-β3 Rabbit Polyclonal Antibody (EAB14036) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Predicted band size: 47 kDa; Observed band size: 13 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol