Polyclonal Antibodies - SORD Rabbit Polyclonal Antibody

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SORD Rabbit Polyclonal Antibody

Catalog #：EAB13997

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB13997-30UL	In Stock	30ul	€115.70
EAB13997-100UL	In Stock	100ul	€258.70
EAB13997-200UL	In Stock	200ul	€440.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

Please select the country you are in to find your local distributor.

	Betaclonal	Phone：+34 (0)91 471 6763
	29/1 Lomonosovsky Pr,	E-mail：tech@betaclonal.com
Spain	Madrid, Spain	Web：www.betaclonal.com

Product Information
Applications	WB, IP, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IP=1:100-500
MW (kDa)	39
Conjugate	Unconjugate
Specificity	SORD Rabbit Polyclonal Antibody detects endogenous levels of SORD protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Sorbitol dehydrogenase; RDH; SDH; XDH; HMNR8; SORD1; SORDD; HEL-S-95n; SORD
Gene Aliases	SORD
UniProt ID	Q00796
Entrez Gene ID	6652

Product Description

SORD(Sorbitol dehydrogenase) also known as SORD1 is a 357 amino acid enzyme that belongs to the zinc-containing alcohol dehydrogenase. SORD plays a crucial role in the metabolism of polyols. SORD is predominantly expressed in the kidney and lens of the eye, where SORD catalyzes the zinc-dependent conversion of sorbitol and xylitol to their corresponding ketoses, utilizing NAD+ as an oxidizing agent. This enzymatic activity is essential for the proper functioning of the sorbitol pathway, which is involved in sugar production and cellular energy metabolism. Disruptions in SORD function can lead to an accumulation of sorbitol, contributing to diabetic complications such as cataracts and microvascular issues.

Product Image Gallery
Western blot analysis of extracts on U2OS, A431 cells, using SORD Rabbit Polyclonal Antibody (EAB13997) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol