Polyclonal Antibodies - SirT6 Rabbit Polyclonal Antibody

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SirT6 Rabbit Polyclonal Antibody

Catalog #：EAB13982

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB13982-100UL	In Stock	100ul	€258.70
EAB13982-200UL	In Stock	200ul	€440.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	SBT BioChem Srl	Phone：+39 05 7156 8147
	Via Ponte di Bagnolo, 811 Bologna,	E-mail：info@sbtbiochem.it
Italy	Italy	Web：www.sbtbiochem.it

Product Information
Applications	WB
Species Reactivity	Human, Mouse
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	39
Conjugate	Unconjugate
Specificity	SirT6 Rabbit Polyclonal Antibody detects endogenous levels of SirT6 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	SIR2-like protein 6; SIRT6; SIR6; Sirtuin-6
Gene Aliases	SIRT6
UniProt ID	Q8N6T7
Entrez Gene ID	50721

Product Description

SIRT6 (also designated Sirtuin 6, SIR2L6) is a 355 amino acid protein that contains one deacetylase sirtuin-type domain and belongs to the sirtuin family. Localized to the nucleus, SIRT6 functions as an NAD+-dependent Histone H3 lysine 9 (H3K9) deacetylase that modulates telomeric chromatin and is involved in DNA repair and telomeric longevity. SIRT6 binds zinc as a cofactor and is expressed as four isoforms that are produced as a result of alternative splicing events.

Product Image Gallery
Western blot analysis of extracts on different cells, using SirT6 Rabbit Polyclonal Antibody (EAB13982) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Lane1: HL60 Lane2: A549 Lane3: Mouse heart Predicted band size: 39 kDa; Observed band size: 39-45 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol