SKU-Pack Size | Availability | Size | Price | |
EAB13932-30UL | In Stock | 30ul | €115.70 | |
EAB13932-100UL | In Stock | 100ul | €258.70 | |
EAB13932-200UL | In Stock | 200ul | €440.70 |
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OlaSciences | Phone£º+33 (0) 9 77 4001 556 |
87, rue des Suisses 65000 Nanterre, | E-mail£ºola@olasciences.com | |
France | France | Web£ºwww.olasciences.com |
Product Information | |
Applications | WB, IHC-P, IF/ICC, ELISA |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000¡¡ IHC-P=1:50-300¡¡ IF/ICC=1:50-300¡¡ |
MW (kDa) | 58 |
Conjugate | Unconjugate |
Specificity | PSAP Rabbit Polyclonal Antibody detects endogenous levels of PSAP protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | PSAP; GLBA; SAP1; Prosaposin |
Gene Aliases | PSAP |
UniProt ID | |
Entrez Gene ID |
Product Description | |
This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
Product Image Gallery | |
![]() Western blot analysis of extracts on different cells, using PSAP Rabbit Polyclonal Antibody (EAB13932) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Lane1: Hela Lane2: NIH/3T3 Lane3: Raw264.7 |
Specific Protocols | |