Polyclonal Antibodies - Cyclophilin A Rabbit Polyclonal Antibody

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Cyclophilin A Rabbit Polyclonal Antibody

Catalog #：EAB13925

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB13925-30UL	In Stock	30ul	€115.70
EAB13925-100UL	In Stock	100ul	€258.70
EAB13925-200UL	In Stock	200ul	€440.70

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email us at info@ebiocell.com

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	SBT BioChem Srl	Phone：+39 05 7156 8147
	Via Ponte di Bagnolo, 811 Bologna,	E-mail：info@sbtbiochem.it
Italy	Italy	Web：www.sbtbiochem.it

Product Information
Applications	WB, IHC-P, IF, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300 IF=1:50-300
MW (kDa)	17
Conjugate	Unconjugate
Specificity	Cyclophilin A Rabbit Polyclonal Antibody detects endogenous levels of Cyclophilin A protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	PPIA; CYPA; CYPH; HEL-S-69p; peptidylprolyl isomerase A
Gene Aliases	PPIA
UniProt ID	P62937
Entrez Gene ID	5478

Product Description

Cyclosporin A also known as PPIase A, CYPA, PPIA is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. Cyclosporin′s intracellular location allows interaction with various cellular components, including the immunosuppressant cyclosporin A (CsA), forming a trimolecular complex alongside calcineurin to inhibit calcineurin phosphatase activity. This inhibition is crucial for regulating T cell activation, making Cyclosporin a key player in immune responses. Additionally, Cyclosporin is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1), where Cyclosporin interacts directly with the capsid domain of the viral Gag polyprotein, facilitating efficient viral replication.

Product Image Gallery

Western blot analysis of extracts on 293, PC12, SH-SY5Y, Jurkat, HepG2, Mouse kidney cells, using Cyclophilin A Rabbit Polyclonal Antibody (EAB13925) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Immunohistochemical analysis of paraffin-embedded Mouse brain tissue, using Cyclophilin A Rabbit Polyclonal Antibody (EAB13925) at 1:100 dilution.

Immunohistochemical analysis of paraffin-embedded Rat brain tissue, using Cyclophilin A Rabbit Polyclonal Antibody (EAB13925) at 1:100 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol