GAS6(Growth arrest specific 6) also known as AXSF is a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation. This gene is frequently overexpressed in many cancers and has been implicated as an adverse prognostic marker. Gas6 plays a crucial role in cell signaling, particularly as a ligand for the receptor tyrosine kinase Axl, which is involved in processes such as cell survival, proliferation, and migration. This interaction helps regulate immune responses and tissue repair, making Gas6 a key player in both normal physiological processes and pathological conditions, including cancer and inflammation.