Polyclonal Antibodies - ETV6/TEL Rabbit Polyclonal Antibody

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ETV6/TEL Rabbit Polyclonal Antibody

Catalog #：EAB13861

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB13861-30UL	In Stock	30ul	$133.50
EAB13861-100UL	In Stock	100ul	$298.50
EAB13861-200UL	In Stock	200ul	$508.50

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email us at info@ebiocell.com

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
United States	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, IHC-P, IF/ICC, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　　 IHC-P=1:50-300　 IF/ICC=1:50-300
MW (kDa)	53
Conjugate	Unconjugate
Specificity	ETV6/TEL Rabbit Polyclonal Antibody detects endogenous levels of ETV6/TEL protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	ETS variant transcription factor 6; TEL; THC5; TEL/ABL; ETV6
Gene Aliases	ETV6
UniProt ID	P41212
Entrez Gene ID	2120

Product Description

TEL also known as ETV6 is an ETS family transcription factor. TEL plays a crucial role in hematopoiesis and is involved in the regulation of gene expression during blood cell development. TEL protein′s importance is underscored by involvement in specific chromosomal translocations associated with human leukemias and sarcomas, which can lead to the disruption of normal cellular functions and contribute to oncogenesis. TEL protein′s ability to bind DNA is facilitated by a highly conserved carboxy terminal domain that contains a sequence related to the SV40 large T antigen nuclear localization signal, allowing TEL to interact with specific DNA motifs, including the 5′-GGAA-3′ element. This interaction is vital for the transcriptional regulation of target genes, making TEL protein a significant player in both normal cellular processes and disease states.

Product Image Gallery

Western blot analysis of extracts on Hela, HepG2, Jurkat cells, using ETV6/TEL Rabbit Polyclonal Antibody (EAB13861) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue, using ETV6/TEL Rabbit Polyclonal Antibody (EAB13861) at 1:200 dilution.

Immunofluorescence analysis of Hela cell, using ETV6/TEL Rabbit Polyclonal Antibody (EAB13861) at 1:200 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol