Polyclonal Antibodies - Phospho-PDK1 (Tyr338) Rabbit Polyclonal Antibody

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Phospho-PDK1 (Tyr338) Rabbit Polyclonal Antibody

Catalog #：EAB13947

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB13947-30UL	In Stock	30ul	€141.70
EAB13947-100UL	In Stock	100ul	€297.70
EAB13947-200UL	In Stock	200ul	€479.70

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email us at info@ebiocell.com

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	Betaclonal	Phone：+34 (0)91 471 6763
	29/1 Lomonosovsky Pr,	E-mail：tech@betaclonal.com
Spain	Madrid, Spain	Web：www.betaclonal.com

Product Information
Applications	WB, IHC-P, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000 IHC-P=1:50-300
MW (kDa)	50
Conjugate	Unconjugate
Specificity	Phospho-PDK1 (Tyr338) Rabbit Polyclonal Antibody detects endogenous levels of PDK1 protein only when phosphorylated at Tyr338.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Pyruvate dehydrogenase kinase 1; PDK1
Gene Aliases	PDK1
UniProt ID	Q15118
Entrez Gene ID	5163

Product Description

PDK1(pyruvate dehydrogenase kinase 1) plays a crucial role in cellular metabolism by regulating the activity of the mitochondrial pyruvate dehydrogenase complex, which is essential for converting pyruvate into acetyl-CoA, a key substrate for the citric acid cycle. This regulation is vital for maintaining energy homeostasis, particularly in response to varying nutrient availability. The activity of PDK1 is influenced by several factors, including the levels of ATP and NADH, which signal the energy status of the cell. PDK1 undergoes post-translational modifications, such as phosphorylation, which can modulate activity and stability, thereby impacting metabolic pathways.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol