Polyclonal Antibodies - CES1 Rabbit Polyclonal Antibody

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CES1 Rabbit Polyclonal Antibody

Catalog #：EAB13754

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB13754-30UL	In Stock	30ul	€115.70
EAB13754-100UL	In Stock	100ul	€258.70
EAB13754-200UL	In Stock	200ul	€440.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	Cambiotech	Phone：+44 (0) 188 448801
	Lanwades Business Park,	E-mail：info@cambiotech.com
Ireland	Kobenhavn K, Ireland	Web：www.cambiotech.com

Product Information
Applications	WB, ELISA
Species Reactivity	Human, Mouse
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	63
Conjugate	Unconjugate
Specificity	CES1 Rabbit Polyclonal Antibody detects endogenous levels of CES1 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Carboxylesterase 1; CEH; REH; TGH; ACAT; CE-1; CES2; HMSE; SES1; HMSE1; PCE-1; hCE-1; CES1
Gene Aliases	CES1
UniProt ID	P23141
Entrez Gene ID	1066

Product Description

CES1 also known as EST1 is a member of the carboxylesterase large family. CES1 plays a vital role in the detoxification processes within the liver, hydrolyzing a variety of xenobiotics and therapeutic pro-drugs, which is essential for drug metabolism and clearance. CES1 is primarily located in the cytosol of liver cells, where CES1 facilitates the breakdown of ester and amide compounds, including narcotics and anti-tumor agents. CES1 localization in the liver is particularly important as CES1 allows for efficient detoxification and metabolism of drugs before they enter systemic circulation, thereby influencing their therapeutic efficacy and safety. Additionally, CES1 exhibits a high affinity for aromatic and aliphatic esters, making CES1 a key player in the metabolism of various therapeutic agents.

Product Image Gallery
Western blot analysis of extracts on A549, Mouse liver cells, using CES1 Rabbit Polyclonal Antibody (EAB13754) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol