Polyclonal Antibodies - ITGAM/CD11b Rabbit Polyclonal Antibody

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ITGAM/CD11b Rabbit Polyclonal Antibody

Catalog #：EAB22570

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22570-100UL	In Stock	100ul	￡218.90

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, IHC-P, IF/ICC
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300 IF/ICC=1:50-300
MW (kDa)	127
Conjugate	Unconjugate
Specificity	CD11b/ITGAM Rabbit Polyclonal Antibody detects endogenous levels of CD11b/ITGAM protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Integrin subunit alpha M; Integrin alpha-M; Integrin αM; CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6; ITGAM
Gene Aliases	ITGAM
UniProt ID	P11215
Entrez Gene ID	3684

Product Description

ITGAM(Integrin alpha-M) also known as CD11b is a cell adhesion molecule. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.

Product Image Gallery

Western blot analysis of extracts on THP-1, Mouse lung, Mouse spleen cells, using CD11b/ITGAM Rabbit Polyclonal Antibody (EAB22570) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Predicted band size: 127 kDa; Observed band size: 170 kDa

Immunohistochemistry of paraffin-embedded Human spleen tissue, using CD11b/ITGAM Rabbit Polyclonal Antibody (EAB22570) at 1:100 dilution.

Immunofluorescence analysis of THP-1 cell, using CD11b/ITGAM Rabbit Polyclonal Antibody (EAB22570) at 1:100 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol