Polyclonal Antibodies - CaSR Rabbit Polyclonal Antibody

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CaSR Rabbit Polyclonal Antibody

Catalog #：EAB11634

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB11634-100UL	In Stock	100ul	￡218.90
EAB11634-200UL	In Stock	200ul	￡372.90

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, IHC-P, IF/ICC, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300　 IF/ICC=1:50-300
MW (kDa)	121
Conjugate	Unconjugate
Specificity	CaSR Rabbit Polyclonal Antibody detects endogenous levels of CaSR protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	CASR; GPRC2A; PCAR1; calcium sensing receptor; CaSR; PCaR1
Gene Aliases	CASR
UniProt ID	P41180
Entrez Gene ID	846

Product Description

Extracellular calcium-sensing receptor (CaSR), also designated parathyroid cell calcium-sensing receptor, is an integral membrane protein that belongs to the G protein-coupled receptor 3 family. CaSR is involved in maintaining a stable calcium concentration by acting as an sensor of the extracellular calcium levels for the parathyroid and kidney. Its activity is mediated by a G protein which activates a phosphatidylinositol-calcium second messenger system. Defects that activate CaSR cause autosomal dominant hypocalcemia, whereas mutations that inactivate the protein cause familial hypocalciuric hypercalcemia. CaSR is expressed mainly in kidney, and is also expressed in intestine, placenta and brain.

Product Image Gallery
Western blot analysis of extracts on LOVO cells, using CaSR Rabbit Polyclonal Antibody (EAB11634) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Predicted band size: 121 kDa; Observed band size: 140 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol