SKU-Pack Size | Availability | Size | Price | |
EAB13707-30UL | In Stock | 30ul | €115.70 | |
EAB13707-100UL | In Stock | 100ul | €258.70 | |
EAB13707-200UL | In Stock | 200ul | €440.70 |
Please select the country you are in to find your local distributor. |
Dianost | Phone£º+49 (0) 40 65472-053 | |
Bullenkoppel 11£¬ 23896 Poggensee, | E-mail£ºola@olasciences.com | |
Germany | Germany | Web£ºwww.olasciences.com |
Product Information | |
Applications | WB, ELISA |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000 |
MW (kDa) | 24 |
Conjugate | Unconjugate |
Specificity | BNIP3L Rabbit Polyclonal Antibody detects endogenous levels of BNIP3L protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
|
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | BNIP3A; BNIP3H; BNIP3L; C86132; D14Ertd719e |
Gene Aliases | BNIP3L |
UniProt ID | |
Entrez Gene ID |
Product Description | |
Bnip3L, which is also designated Nip3L or Nix, is highly related to Nip3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins. The encoded protein binds to Bcl-2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release of cytochrome c. Nip3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL. |
Product Image Gallery | |
Western blot analysis of extracts on HCT116 cells, using BNIP3L Rabbit Polyclonal Antibody (EAB13707) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
Specific Protocols | |