SKU-Pack Size | Availability | Size | Price | |
EAB13623-100UL | In Stock | 100ul | €258.70 | |
EAB13623-200UL | In Stock | 200ul | €440.70 |
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SBT BioChem Srl | Phone£º+39 05 7156 8147 | |
Via Ponte di Bagnolo, 811 Bologna, | E-mail£ºinfo@sbtbiochem.it | |
Italy | Italy | Web£ºwww.sbtbiochem.it |
Product Information | |
Applications | IF/ICC |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | IF/ICC=1:50-300¡¡ |
Conjugate | Unconjugate |
Specificity | 5-Methylcytosine (5-mC) Rabbit Polyclonal Antibody detects endogenous levels of 5-Methylcytosine (5-mC) protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | 5-mC; 5-meC; 5-Methyl-cytosine; 5mc |
Product Description | |
Methylation of DNA cytosine bases plays important roles in the regulation of gene transcription. It has been estimated that 60 to 90% of the cytosines in CpG dinucleotides are methylated. An increase in methyl-CpG correlates with transcriptional silencing for the whole chromosome especially in developmentally regulated genes. Methylation is believed to lead to transcriptional silencing by multiple mechanisms including alteration of transcription factor binding to promoters and alteration in chromatin structure. |
Specific Protocols | |