P05787

Cytokeratin 8 also known as Keratin 8, CK8, KRT8 is a vital component of the cytoskeletal structure in epithelial cells. Cytokeratin 8 playing a crucial role in maintaining cellular integrity and providing mechanical support. Cytokeratin 8 is predominantly located in the cytoplasm of simple epithelial cells, where Cytokeratin 8 forms intermediate filaments that contribute to the overall architecture of the tissue. Cytokeratin 8 presence is particularly important in epithelial differentiation and tissue specialization, serving as a marker for various epithelial-derived tumors. Notably, abnormal Cytokeratin 8 expression has been associated with squamous cell carcinomas, indicating a potential role in tumor progression and malignancy.