Monoclonal Antibodies - IRF-3 Mouse Monoclonal Antibody

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IRF-3 Mouse Monoclonal Antibody

Catalog #：EAB13551

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB13551-30UL	In Stock	30ul	$133.50
EAB13551-100UL	In Stock	100ul	$298.50
EAB13551-200UL	In Stock	200ul	$508.50

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
United States	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, IHC-P
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:1000-5000　 IHC-P=1:100-500
MW (kDa)	47
Conjugate	Unconjugate
Specificity	IRF-3 Mouse Monoclonal Antibody detects endogenous levels of IRF-3 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Interferon regulatory factor 3; IIAE7; IRF3
Gene Aliases	IRF3
UniProt ID	Q14653
Entrez Gene ID	3661

Product Description

IRF-3 is a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7.

Product Image Gallery

Western blot analysis of extracts on MCF7, Mouse heart, Rat heart cells, using IRF-3 Mouse Monoclonal Antibody (EAB13551) at 1:2000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.

Predicted band size: 47 kDa; Observed band size: 45-55 kDa

Immunohistochemical analysis of paraffin-embedded Human tonsil tissue, using IRF-3 Mouse Monoclonal Antibody (EAB13551) at 1:200 dilution.

Immunohistochemical analysis of paraffin-embedded Human spleen tissue, using IRF-3 Mouse Monoclonal Antibody (EAB13551) at 1:200 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol