SKU-Pack Size | Availability | Size | Price | |
EAB13551-30UL | In Stock | 30ul | €115.70 | |
EAB13551-100UL | In Stock | 100ul | €258.70 | |
EAB13551-200UL | In Stock | 200ul | €440.70 |
Please select the country you are in to find your local distributor. |
Dianost | Phone£º+49 (0) 40 65472-053 | |
Bullenkoppel 11£¬ 23896 Poggensee, | E-mail£ºola@olasciences.com | |
Germany | Germany | Web£ºwww.olasciences.com |
Product Information | |
Applications | WB, IHC-P |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Mouse IgG1 |
Clonality | Monoclonal |
Applications Dilutions | WB=1:1000-5000¡¡ IHC-P=1:100-500¡¡ |
MW (kDa) | 47 |
Conjugate | Unconjugate |
Specificity | IRF-3 Mouse Monoclonal Antibody detects endogenous levels of IRF-3 protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
|
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | Interferon regulatory factor 3; IIAE7; IRF3 |
Gene Aliases | IRF3 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
IRF-3 is a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7. |
Product Image Gallery | |
Western blot analysis of extracts on MCF7, Mouse heart, Rat heart cells, using IRF-3 Mouse Monoclonal Antibody (EAB13551) at 1:2000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Predicted band size: 47 kDa; Observed band size: 45-55 kDa Immunohistochemical analysis of paraffin-embedded Human tonsil tissue, using IRF-3 Mouse Monoclonal Antibody (EAB13551) at 1:200 dilution.
Immunohistochemical analysis of paraffin-embedded Human spleen tissue, using IRF-3 Mouse Monoclonal Antibody (EAB13551) at 1:200 dilution.
|
Specific Protocols | |