SKU-Pack Size | Availability | Size | Price | |
EAB13515-30UL | In Stock | 30ul | $133.50 | |
EAB13515-100UL | In Stock | 100ul | $298.50 | |
EAB13515-200UL | In Stock | 200ul | $508.50 |
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EbioCell | Phone:(540) 808-3925 | |
Imperial Business Park 4819 Emperor Boulevard, | E-mail:order@ebiocell.com | |
Canada | Suite 408 Durham, NC 27703, USA | Web:www.ebiocell.com |
Product Information | |
Applications | WB, IHC-P, IF, ELISA |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
MW (kDa) | 37 |
Conjugate | Unconjugate |
Specificity | Cdk6 Rabbit Polyclonal Antibody detects endogenous levels of Cdk6 protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | CDK6; MCPH12; PLSTIRE; cyclin-dependent kinase 6; CDKN6; Crk2 |
Gene Aliases | CDK6 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
The protein encoded by this gene is a member of the CMGC family of serine/threonine protein kinases. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Altered expression of this gene has been observed in multiple human cancers. A mutation in this gene resulting in reduced cell proliferation, and impaired cell motility and polarity, and has been identified in patients with primary microcephaly. |
Product Image Gallery | |
Western blot analysis of extracts on different cells, using Cdk6 Rabbit Polyclonal Antibody (EAB13515) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Lane1: SH-SY5Y Lane2: Jurkat Lane3: U2OS Immunohistochemical analysis of paraffin-embedded Human tonsil tissue, using Cdk6 Rabbit Polyclonal Antibody (EAB13515) at 1:200 dilution.
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue, using Cdk6 Rabbit Polyclonal Antibody (EAB13515) at 1:200 dilution.
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Specific Protocols | |