Polyclonal Antibodies - EAAT1 Rabbit Polyclonal Antibody

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EAAT1 Rabbit Polyclonal Antibody

Catalog #：EAB13511

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB13511-30UL	In Stock	30ul	￡97.90
EAB13511-100UL	In Stock	100ul	￡218.90
EAB13511-200UL	In Stock	200ul	￡372.90

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email us at info@ebiocell.com

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	60
Conjugate	Unconjugate
Specificity	EAAT1 Rabbit Polyclonal Antibody detects endogenous levels of EAAT1 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	EA6; EAAT1; GLAST; GLAST1; GLU-T; GluT-1; Gmt1; MGluT1; SLC1A3; EAA1; GLAST-1; SLC1A-3; EAAT-1; Excitatory amino acid transporter 1
Gene Aliases	SLC1A3
UniProt ID	P43003
Entrez Gene ID	6507

Product Description

EAAT1 (also designated Excitatory amino acid transporter 1, SLC1A3) is one of the two glial glutamate transporters that clear the extracellular glutamate generated during neuronal signal transmission. Excitatory amino acid transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic acction of glutamate. The reuptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters.

Product Image Gallery
Western blot analysis of extracts on Hela cells, using EAAT1 Rabbit Polyclonal Antibody (EAB13511) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Predicted band size: 60 kDa; Observed band size: 65 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol