Polyclonal Antibodies - Phospho-SF3B1/SAP 155 (Thr313) Rabbit Polyclonal Antibody

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Phospho-SF3B1/SAP 155 (Thr313) Rabbit Polyclonal Antibody

Catalog #：EAB13356

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB13356-30UL	In Stock	30ul	€141.70
EAB13356-100UL	In Stock	100ul	€297.70
EAB13356-200UL	In Stock	200ul	€479.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	Dianost	Phone：+49 (0) 40 65472-053
	Bullenkoppel 11， 23896 Poggensee,	E-mail：ola@olasciences.com
Germany	Germany	Web：www.olasciences.com

Product Information
Applications	WB, IHC-P
Species Reactivity	Human, Mouse
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300
MW (kDa)	145
Conjugate	Unconjugate
Specificity	Phospho-SF3B1/SAP 155 (Thr313) Rabbit Polyclonal Antibody detects endogenous levels of SF3B1/SAP 155 protein only when phosphorylated at Thr313.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Splicing factor 3b subunit 1; MDS; PRP10; Hsh155; PRPF10; SAP155; SF3b155; SF3B1
Gene Aliases	SF3B1
UniProt ID	O75533
Entrez Gene ID	23451

Product Description

SF3B1 also known as SAP 155 is a crucial component of the SF3b complex, which is associated with the U2 small nuclear ribonucleoprotein (snRNP) and plays an essential role in spliceosome assembly. This complex is vital for the splicing of pre-mRNA, a process that is critical for the proper expression of genes. The interaction of SAP 145 with other spliceosomal proteins, such as SAP 49, SAP 130, and SAP 155, highlights SAP 145′s importance in the formation and stability of the spliceosome. Notably, the direct interaction between SAP 49 and SAP 145 is mediated by the amino-terminus of SAP 49, which contains two RNA-recognition motifs, suggesting this interaction is integral to the complex′s ability to tether U2 snRNP to the branch site during splicing.

Product Image Gallery
Western blot analysis of extracts on Hela cells treated with Heat Shock, using Phospho-SF3B1/SAP 155 (Thr313) Rabbit Polyclonal Antibody (EAB13356) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol