P78504

Jagged1 also known as JAG1, CD339 is a type I membrane-anchored multidomain protein and a ligand of the Notch receptor. Jagged1 plays a crucial role in the Notch signaling pathway, which is essential for various developmental processes, including cell fate determination and tissue differentiation. Specifically, Jagged1 acts as a ligand for Notch receptors, facilitating communication between adjacent cells and influencing developmental pathways. This interaction is particularly important in cardiovascular development and hematopoiesis, where Jagged1 helps regulate the balance between cell proliferation and differentiation.