SKU-Pack Size | Availability | Size | Price | |
EAB13119-30UL | In Stock | 30ul | €115.70 | |
EAB13119-100UL | In Stock | 100ul | €258.70 | |
EAB13119-200UL | In Stock | 200ul | €440.70 |
Please select the country you are in to find your local distributor. |
Betaclonal | Phone£º+34 (0)91 471 6763 | |
29/1 Lomonosovsky Pr, | E-mail£ºtech@betaclonal.com | |
Spain | Madrid, Spain | Web£ºwww.betaclonal.com |
Product Information | |
Applications | WB, IHC-P |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Mouse IgG1 |
Clonality | Monoclonal |
Applications Dilutions | WB=1:1000-5000¡¡ IHC-P=1:50-300 |
MW (kDa) | 19 |
Conjugate | Unconjugate |
Specificity | Cofilin Mouse Monoclonal Antibody detects endogenous levels of Cofilin protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | CFL; CFL1; Cof; cofilin; HEL-S-15; n-cofilin; Cofilin1; 18 kDa phosphoprotein; p18; CFL-1; Cofilin-1 |
Gene Aliases | CFL1 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. |
Product Image Gallery | |
Western blot analysis of extracts on Hela cells, using Cofilin Mouse Monoclonal Antibody (EAB13119) at 1:2000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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Specific Protocols | |