Polyclonal Antibodies - Phospho-DNA-PKcs (Thr2647) Rabbit Polyclonal Antibody

Location：Home > Antibodies > Primary Antibodies > Polyclonal Antibodies

Phospho-DNA-PKcs (Thr2647) Rabbit Polyclonal Antibody

Catalog #：EAB13107

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB13107-30UL	In Stock	30ul	€141.70
EAB13107-100UL	In Stock	100ul	€297.70
EAB13107-200UL	In Stock	200ul	€479.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

Please select the country you are in to find your local distributor.

	SBT BioChem Srl	Phone：+39 05 7156 8147
	Via Ponte di Bagnolo, 811 Bologna,	E-mail：info@sbtbiochem.it
Italy	Italy	Web：www.sbtbiochem.it

Product Information
Applications	WB, IHC-P, IF/ICC, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300　 IF/ICC=1:50-300
MW (kDa)	469
Conjugate	Unconjugate
Specificity	Phospho-DNA-PKcs (Thr2647) Rabbit Polyclonal Antibody detects endogenous levels of DNA-PKcs protein only when phosphorylated at Thr2647.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	DNA-dependent protein kinase catalytic subunit; DNA-PKcs; HYRC; p350; DNAPK; DNPK1; HYRC1; IMD26; S473K; XRCC7; DNAPKc; DNA-PKC; PRKDC
Gene Aliases	PRKDC
UniProt ID	P78527
Entrez Gene ID	5591

Product Description

DNA-PKcs also known as XRCC7, DNAPK, PRKDC is a critical component of the DNA-dependent protein kinase complex, DNA-PKcs plays a crucial role in the repair of DNA double-strand breaks (DSBs) and is essential for V(D)J recombination, a process vital for the development of immune diversity. Located in the nucleus, DNA-PKcs forms a heterotrimeric complex with Ku proteins, which are responsible for recognizing and binding to DSBs, thereby facilitating repair processes. Proper functioning of DNA-PKcs is critical, as defects can lead to severe consequences, including increased sensitivity to ionizing radiation and impaired DNA repair mechanisms, which are associated with various genetic disorders and cancers.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol