Q9BXM7

PINK1 is a crucial member of the serine/threonine protein kinase family and functions as a tumor suppressor. PINK1 is primarily localized in mitochondria, where PINK1 plays a vital role in maintaining mitochondrial integrity and function. PINK1′s presence in mitochondria helps protect cells from mitochondrial dysfunction, particularly during cellular stress, by phosphorylating mitochondrial proteins essential for energy production and apoptosis regulation. PINK1′s widespread expression in tissues such as testis, skeletal muscle, and heart underscores PINK1′s importance in various physiological processes, while lower expression in tissues like pancreas and brain highlights specialized roles in cellular health and disease.