Monoclonal Antibodies - Acetyl-Histone H3 (Lys27) Rabbit Monoclonal Antibody

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Acetyl-Histone H3 (Lys27) Rabbit Monoclonal Antibody

Catalog #：EAB23704

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB23704-100UL	In Stock	100ul	$343.50

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
Canada	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, IP, IHC-P, IF/ICC, ChIP
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:1000-5000　 IP=1:10-100 IHC-P=1:100-500 IF/ICC=1:100-500 ChIP=1:10-100
MW (kDa)	15
Conjugate	Unconjugate
Specificity	Acetyl-Histone H3 (Lys27) Rabbit Monoclonal Antibody detects endogenous levels of histone H3 protein only when acetylated at Lys27.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	H3 clustered histone 1; H3/A; H31; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3FA; H3C10; H3C11; H3C12; Histone H3; H3K27AC
Gene Aliases	H3K27AC
UniProt ID	P68431
Entrez Gene ID	8350

Product Description

Histone H3 is one of the four core histones (H2A, H2B, H3, and H4) essential for the formation of nucleosomes, which are fundamental units of chromatin structure in eukaryotic cells. Histone H3 is a core part of the nucleosome′s octameric structure that wraps DNA, regulating gene expression and DNA replication. Histone H3 plays a crucial role in chromatin′s structural organization, essential for DNA packaging within the nucleus. Histone H3 maintains genomic stability and facilitates transcription and repair processes. Histone H3 undergoes various post-translational modifications, including methylation and acetylation, influencing DNA and protein interactions, affecting chromatin structure and function. These modifications regulate gene expression and impact cellular differentiation and environmental response.

Product Image Gallery
Western blot analysis of extracts on C6 cells, using Acetyl-Histone H3 (Lys27) Rabbit Monoclonal Antibody (EAB23704) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Predicted band size: 15 kDa; Observed band size: 15-17 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol