| SKU-Pack Size | Availability | Size | Price | |
| EAB22288-100UL | In Stock | 100ul | €297.70 |
| Please select the country you are in to find your local distributor. |
| Betaclonal | Phone£º+34 (0)91 471 6763 | |
| 29/1 Lomonosovsky Pr, | E-mail£ºtech@betaclonal.com | |
| Spain | Madrid, Spain | Web£ºwww.betaclonal.com |
| Product Information | |
| Applications | WB, IHC-P, IF/ICC, FC |
| Species Reactivity | Human |
| Host / Isotype | Rabbit IgG |
| Clonality | Monoclonal |
| Applications Dilutions | WB=1:500-2000¡¡ IHC-P=1:100-500 IF/ICC=1:50-200 FC=1:10-100 |
| MW (kDa) | 147 |
| Conjugate | Unconjugate |
| Specificity | CD45 Rabbit Monoclonal Antibody detects endogenous levels of CD45 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
| Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
| Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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| Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
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| Product Bioinformatics | |
| Synonym(s) | Protein tyrosine phosphatase receptor type C; LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; IMD105; PTPRC |
| Gene Aliases | PTPRC |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CD45 also known as LCA, GP180, B220, LY5, PTPRC is a member of the protein tyrosine phosphatase (PTP) family. CD45 is a transmembrane glycoprotein that is universally expressed on all nucleated hematopoietic cells, making it a critical marker for identifying and studying various immune cell populations. Located on the cell surface, CD45 plays an essential role in modulating signal transduction pathways by regulating tyrosine phosphorylation, which is pivotal for T and B cell receptor signaling and overall immune cell activation. This strategic cellular positioning allows CD45 to interact directly with key signaling molecules, thereby influencing immune responses and maintaining cellular communication within the immune system. |
| Product Image Gallery | |
![]() Western blot analysis of extracts on Raji, Jurkat cells, using CD45 Rabbit Monoclonal Antibody (EAB22288) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 147 kDa; Observed band size: 180-250 kDa |
| Specific Protocols | |