Recombinant Antibodies - CD45 Rabbit Monoclonal Antibody

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CD45 Rabbit Monoclonal Antibody

Catalog #：EAB22288

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22288-100UL	In Stock	100ul	€297.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	Dianost	Phone：+49 (0) 40 65472-053
	Bullenkoppel 11， 23896 Poggensee,	E-mail：ola@olasciences.com
Germany	Germany	Web：www.olasciences.com

Product Information
Applications	WB, IHC-P, IF/ICC, FC
Species Reactivity	Human
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:100-500 IF/ICC=1:50-200 FC=1:10-100
MW (kDa)	147
Conjugate	Unconjugate
Specificity	CD45 Rabbit Monoclonal Antibody detects endogenous levels of CD45 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Protein tyrosine phosphatase receptor type C; LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; IMD105; PTPRC
Gene Aliases	PTPRC
UniProt ID	P08575
Entrez Gene ID	5788

Product Description

CD45 also known as LCA, GP180, B220, LY5, PTPRC is a member of the protein tyrosine phosphatase (PTP) family. CD45 is a transmembrane glycoprotein that is universally expressed on all nucleated hematopoietic cells, making it a critical marker for identifying and studying various immune cell populations. Located on the cell surface, CD45 plays an essential role in modulating signal transduction pathways by regulating tyrosine phosphorylation, which is pivotal for T and B cell receptor signaling and overall immune cell activation. This strategic cellular positioning allows CD45 to interact directly with key signaling molecules, thereby influencing immune responses and maintaining cellular communication within the immune system.

Product Image Gallery
Western blot analysis of extracts on Raji, Jurkat cells, using CD45 Rabbit Monoclonal Antibody (EAB22288) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Predicted band size: 147 kDa; Observed band size: 180-250 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol