Polyclonal Antibodies - Sema4D/CD100 Rabbit Polyclonal Antibody

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Sema4D/CD100 Rabbit Polyclonal Antibody

Catalog #：EAB11858

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB11858-30UL	In Stock	30ul	€115.70
EAB11858-100UL	In Stock	100ul	€258.70
EAB11858-200UL	In Stock	200ul	€440.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	OlaSciences	Phone：+33 (0) 9 77 4001 556
	87, rue des Suisses 65000 Nanterre,	E-mail：ola@olasciences.com
France	France	Web：www.olasciences.com

Product Information
Applications	WB, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	95
Conjugate	Unconjugate
Specificity	Sema4D/CD100 Rabbit Polyclonal Antibody detects endogenous levels of Sema4D/CD100 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	CD100; SEMA4D; Semaphorin-4D; Semaphorin4D
Gene Aliases	SEMA4D
UniProt ID	Q92854
Entrez Gene ID	10507

Product Description

Semaphorin-4D (CD100) is a transmembrane protein belonging to group IV of the semaphorin family. CD100 is expressed in both embryonic and adult kidney, heart, lung and neural tissues. Plexin-B1, a receptor expressed abundantly in fetal brain and kidney, binds CD100 with high affinity. CD100 is the only member of the semaphorin family that is expressed in the immune system. CD100 activates T cell proliferation and promotes B cell aggregation. CD100 regulates B cell response by negating an inhibitory signal from CD72 that normally diminishes B cell response. This signal is turned off when CD100 binds to CD72 and induces tyrosine dephosphorylation of CD72, followed by the dissociation of SHP-1 from CD72. The gene encoding human CD100 maps to chromosome 9q22.2.

Product Image Gallery
Western blot analysis of extracts on different cells, using Sema4D/CD100 Rabbit Polyclonal Antibody (EAB11858) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Lane1: L929 Lane2: MCF7

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol