Serine racemase also known as SRR is an enzyme that catalyzes the interconversion of L-serine and D-serine, a key endogenous co-agonist at NMDA-type glutamate receptors. Serine racemase plays a crucial role in studying the central nervous system by detecting proteins that catalyze the conversion of L-serine to D-serine, a significant endogenous co-agonist of N-methyl-D-aspartate (NMDA) receptors, which are essential for synaptic plasticity, learning, and memory. The presence of D-serine in the mammalian brain highlights its importance in neurotransmission and neurodevelopment, as well as its involvement in neurodegenerative diseases.