SKU-Pack Size | Availability | Size | Price | |
EAB22129-100UL | In Stock | 100ul | €336.70 |
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Dianost | Phone£º+49 (0) 40 65472-053 |
Bullenkoppel 11£¬ 23896 Poggensee, | E-mail£ºola@olasciences.com | |
Germany | Germany | Web£ºwww.olasciences.com |
Product Information | |
Applications | WB, IHC-P |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Mouse IgG2b |
Clonality | Monoclonal |
Applications Dilutions | WB=1:5000-20000¡¡ IF/ICC=1:100-500¡¡ |
MW (kDa) | 161 |
Conjugate | Unconjugate |
Specificity | ROCK2 Mouse Monoclonal Antibody detects endogenous levels of ROCK2 protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | 230113H15Rik; KIAA0619; mKIAA0619; Rho-kinase; ROCK-II; ROCK2; Rock2m; ROK; ROKalpha |
Gene Aliases | ROCKII |
UniProt ID | |
Entrez Gene ID |
Product Description | |
Rho, the Ras-related small GTPase, is responsible for the regulation of Actin-based cytoskeletal structures, including stress fibers, focal adhesions and the contractile ring apparatus. Rho proteins function as molecular switches that are able to turn cytokinesis on and off. Although little is known about signaling downstream of Rho, a host of putative Rho effector proteins have been de-scribed, including rhophilin, Rhotekin, citron and the serine/threonine kinase, protein kinase N. Two additional Rho-activated serine/threonine kinases have been described, designated Rock-1 and Rock-2 (also referred to as Roka) for Rho-associated coil-containing protein kinase. Rock-1 and Rock-2 share a structural similarity with myotonic dystrophy kinase. |
Product Image Gallery | |
![]() Western blot analysis of extracts on different cells, using ROCK2 Mouse Monoclonal Antibody (EAB22129) at 1:10000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Lane1: Hela Lane2: Jurkat Lane3: NIH/3T3 |
Specific Protocols | |