Recombinant Antibodies - Phospho-PAK4/PAK5/PAK6 (Ser474/Ser602/Ser560) Rabbit Monoclonal Antibody

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Phospho-PAK4/PAK5/PAK6 (Ser474/Ser602/Ser560) Rabbit Monoclonal Antibody

Catalog #：EAB22153

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22153-100UL	In Stock	100ul	€336.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	OlaSciences	Phone：+33 (0) 9 77 4001 556
	87, rue des Suisses 65000 Nanterre,	E-mail：ola@olasciences.com
France	France	Web：www.olasciences.com

Product Information
Applications	WB
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	64, 80, 75
Conjugate	Unconjugate
Specificity	Phospho-PAK4/PAK5/PAK6 (Ser474/Ser602/Ser560) Rabbit Monoclonal Antibody detects endogenous levels of PAK4/PAK5/PAK6 only when phosphorylated at Ser474/602/560.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	KIAA1142; KIAA1264; PAK4; PAK5; PAK6; PAK7
Gene Aliases	PAK4/PAK5/PAK6
UniProt ID	O96013, Q9P286, Q9NQU5
Entrez Gene ID	10298, 57144, 56924

Product Description

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.

Product Image Gallery
Western blot analysis of extracts on Hela, A549 cells, using Phospho-PAK4/PAK5/PAK6 (Ser474/Ser602/Ser560) Rabbit Monoclonal Antibody (EAB22153) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol