Monoclonal Antibodies - MFN1/Mitofusin-1 Mouse Monoclonal Antibody

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MFN1/Mitofusin-1 Mouse Monoclonal Antibody

Catalog #：EAB22139

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22139-100UL	In Stock	100ul	€336.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

Please select the country you are in to find your local distributor.

	Cambiotech	Phone：+44 (0) 188 448801
	Lanwades Business Park,	E-mail：info@cambiotech.com
Ireland	Kobenhavn K, Ireland	Web：www.cambiotech.com

Product Information
Applications	WB, IHC-P, IF/ICC, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Mouse IgG2a
Clonality	Monoclonal
Applications Dilutions	WB=1:1000-5000 IHC-P=1:100-500 IF/ICC=1:100-500
MW (kDa)	84
Conjugate	Unconjugate
Specificity	MFN1/Mitofusin-1 Mouse Monoclonal Antibody detects endogenous levels of MFN1/Mitofusin-1 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Mitofusin 1; hfzo1; hfzo2; MFN1
Gene Aliases	MFN1
UniProt ID	Q8IWA4
Entrez Gene ID	55669

Product Description

MFN1(Mitofusin 1) is a mediator of mitochondrial fusion. MFN1 plays a crucial role in mitochondrial dynamics, specifically in mitochondrial fusion, which is essential for maintaining mitochondrial function and cellular energy metabolism. MFN1 localizes to the outer mitochondrial membrane and forms high molecular weight protein complexes that facilitate mitochondrial fusion, a process vital for cellular health and stress adaptation. MFN1 contains a GTPase domain critical for function, with purified recombinant MFN1 showing approximately eightfold higher GTPase activity compared to MFN2. This activity difference may influence distinct roles of MFN1 and MFN2 in cellular processes, including varying expression levels across tissues, with MFN1 transcripts being particularly elevated in heart tissue.

Product Image Gallery
Western blot analysis of extracts on K562, HepG2, Jurkat, NIH/3T3 cells, using MFN1/Mitofusin-1 Mouse Monoclonal Antibody (EAB22139) at 1:3000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol