SKU-Pack Size | Availability | Size | Price | |
EAB14782-30UL | In Stock | 30ul | €115.70 | |
EAB14782-100UL | In Stock | 100ul | €258.70 | |
EAB14782-200UL | In Stock | 200ul | €440.70 |
Please select the country you are in to find your local distributor. |
Betaclonal | Phone£º+34 (0)91 471 6763 | |
29/1 Lomonosovsky Pr, | E-mail£ºtech@betaclonal.com | |
Spain | Madrid, Spain | Web£ºwww.betaclonal.com |
Product Information | |
Applications | WB, IP, ELISA |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000¡¡ IP=1:100-500¡¡ |
MW (kDa) | 24 |
Conjugate | Unconjugate |
Specificity | MAD2L1 Rabbit Polyclonal Antibody detects endogenous levels of MAD2L1 protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | HSMAD2; MAD-2; MAD2like1; MAD2 mitotic arrest deficient like 1; MAD2B; MAD2L1; Mitotic arrest deficient 2; REV7; MD2L1; MAD2 |
Gene Aliases | MAD2L1 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
MAD2L1 (also designated MAD2) is a component of the mitotic spindle checkpoint. Cells with mutated MAD2 do not undergo mitotic arrest in response to incorrect spindle fiber assembly, which results in missegregation and eventual cell death. MAD2L1 is localized to unattached kinetochores during prometaphase and disassociates upon spindle fiber attachment, indicating that MAD2L1 regulates kinetochore binding to the spindle fibers. Human MAD2L1 has also been shown to associate with insulin receptor (IR), but not IGFIR, implicating MAD2L1 as a mediator for IR-specific signaling. |
Product Image Gallery | |
Western blot analysis of extracts on different cells, using MAD2L1 Rabbit Polyclonal Antibody (EAB14782) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Lane1: K562 Lane2: A549 Lane3: HuvEc |
Specific Protocols | |