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MAD2L1 Rabbit Polyclonal Antibody
Catalog #£ºEAB14782
  SKU-Pack Size Availability Size Price
EAB14782-30UL In Stock 30ul €115.70
EAB14782-100UL In Stock 100ul €258.70
EAB14782-200UL In Stock 200ul €440.70
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Product Information
Applications WB, IP, ELISA
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit IgG
Clonality Polyclonal
Applications Dilutions WB=1:500-2000¡¡
IP=1:100-500¡¡
MW (kDa) 24
Conjugate Unconjugate
Specificity MAD2L1 Rabbit Polyclonal Antibody detects endogenous levels of MAD2L1 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) HSMAD2; MAD-2; MAD2like1; MAD2 mitotic arrest deficient like 1; MAD2B; MAD2L1; Mitotic arrest deficient 2; REV7; MD2L1; MAD2
Gene Aliases MAD2L1
UniProt ID

Q13257

Entrez Gene ID

4085

Product Description

MAD2L1 (also designated MAD2) is a component of the mitotic spindle checkpoint. Cells with mutated MAD2 do not undergo mitotic arrest in response to incorrect spindle fiber assembly, which results in missegregation and eventual cell death. MAD2L1 is localized to unattached kinetochores during prometaphase and disassociates upon spindle fiber attachment, indicating that MAD2L1 regulates kinetochore binding to the spindle fibers. Human MAD2L1 has also been shown to associate with insulin receptor (IR), but not IGFIR, implicating MAD2L1 as a mediator for IR-specific signaling.

Product Image Gallery
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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