Polyclonal Antibodies - LXRα Rabbit Polyclonal Antibody

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LXRα Rabbit Polyclonal Antibody

Catalog #：EAB11792

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB11792-30UL	In Stock	30ul	￡97.90
EAB11792-100UL	In Stock	100ul	￡218.90
EAB11792-200UL	In Stock	200ul	￡372.90

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, IHC-P, IF, ELISA
Species Reactivity	Human, Mouse, Rat, Golden hamster
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300　 IF=1:50-300
MW (kDa)	50
Conjugate	Unconjugate
Specificity	LXRα Rabbit Polyclonal Antibody detects endogenous levels of LXRα protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Liver X receptor alpha; LXR-a; LXRA; NR1H3; NR1H-3; RLD-1; RLD
Gene Aliases	NR1H3
UniProt ID	Q13133
Entrez Gene ID	10062

Product Description

The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Product Image Gallery

Western blot analysis of extracts on different cells, using LXRα Rabbit Polyclonal Antibody (EAB11792) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Lane1: Hela
Lane2: HepG2
Lane3: THP-1

Immunohistochemical analysis of paraffin-embedded Mouse brain tissue, using LXRα Rabbit Polyclonal Antibody (EAB11792) at 1:100 dilution.

Immunohistochemical analysis of paraffin-embedded Rat brain tissue, using LXRα Rabbit Polyclonal Antibody (EAB11792) at 1:100 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol