Polyclonal Antibodies - ITPA Rabbit Polyclonal Antibody

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ITPA Rabbit Polyclonal Antibody

Catalog #：EAB14472

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB14472-30UL	In Stock	30ul	€115.70
EAB14472-100UL	In Stock	100ul	€258.70
EAB14472-200UL	In Stock	200ul	€440.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	SBT BioChem Srl	Phone：+39 05 7156 8147
	Via Ponte di Bagnolo, 811 Bologna,	E-mail：info@sbtbiochem.it
Italy	Italy	Web：www.sbtbiochem.it

Product Information
Applications	WB, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	21
Conjugate	Unconjugate
Specificity	ITPA Rabbit Polyclonal Antibody detects endogenous levels of ITPA protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Inosine triphosphatase; DEE35; My049; ITPase; NTPase; C20orf37; dJ794I6.3; HLC14-06-P; ITPA
Gene Aliases	ITPA
UniProt ID	Q9BY32
Entrez Gene ID	3704

Product Description

ITPA is also known as ITPase is a 194 amino acid protein. ITPA plays a crucial role in nucleotide metabolism by catalyzing the conversion of inosine triphosphate (ITP) and deoxyinosine triphosphate (dITP) into inosine monophosphate (IMP) and diphosphate. This enzymatic activity is vital for maintaining the balance of nucleotide pools within the cell, as an excess of ITP can lead to cellular dysfunction and has been implicated in various pathological conditions. ITPA is predominantly localized in the cytoplasm and is highly expressed in tissues such as the heart, liver, sex glands, thyroid, and adrenal glands. Deficiencies in ITPA can result in an accumulation of ITP in erythrocytes, leukocytes, and fibroblasts, which is thought to be inherited and can lead to significant metabolic disturbances.

Product Image Gallery
Western blot analysis of extracts on Hela cells, using ITPA Rabbit Polyclonal Antibody (EAB14472) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol