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hnRNP Q Rabbit Polyclonal Antibody
Catalog #:EAB11776
  SKU-Pack Size Availability Size Price
EAB11776-30UL In Stock 30ul �115.70
EAB11776-100UL In Stock 100ul �258.70
EAB11776-200UL In Stock 200ul �440.70
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Product Information
Applications WB, IHC-P, IF/ICC, ELISA
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit IgG
Clonality Polyclonal
Applications Dilutions WB=1:500-2000 
IHC-P=1:50-300 
IF/ICC=1:50-300 
MW (kDa) 70
Conjugate Unconjugate
Specificity hnRNP Q Rabbit Polyclonal Antibody detects endogenous levels of hnRNP Q protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) Synaptotagmin binding cytoplasmic RNA interacting protein; PP68; NSAP1; GRYRBP; HNRNPQ; HNRPQ1; GRY-RBP; hnRNP-Q; SYNCRIP
Gene Aliases SYNCRIP
UniProt ID

O60506

Entrez Gene ID

10492

Product Description

hnRNP Q also known as HNRNPQ, SYNCRIP is a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNP Q plays a pivotal role in RNA processing, particularly in regulating pre-mRNA splicing, which is essential for proper gene expression. hnRNP Q is widely expressed across different tissues and is developmentally regulated, highlighting its importance in various biological processes. hnRNP Q interacts with several key proteins, including survival motor neuron protein (SMN), which is crucial for motor neuron health. Disruption of hnRNP Q and SMN interaction due to genetic mutations can lead to spinal muscular atrophy, a severe neurodegenerative disorder. Additionally, hnRNP Q exhibits a unique expression pattern, being upregulated after midnight, which correlates with a decline in AANAT, the enzyme responsible for melatonin synthesis.

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Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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