Polyclonal Antibodies - GSDMD (N-ternal) Rabbit Polyclonal Antibody

Location：Home > Antibodies > Primary Antibodies > Polyclonal Antibodies

GSDMD (N-ternal) Rabbit Polyclonal Antibody

Catalog #：EAB10722

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB10722-30UL	In Stock	30ul	€115.70
EAB10722-100UL	In Stock	100ul	€258.70
EAB10722-200UL	In Stock	200ul	€440.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

Please select the country you are in to find your local distributor.

	OlaSciences	Phone：+33 (0) 9 77 4001 556
	87, rue des Suisses 65000 Nanterre,	E-mail：ola@olasciences.com
France	France	Web：www.olasciences.com

Product Information
Applications	WB, IHC-P, IF/ICC
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300 IF/ICC=1:50-300
MW (kDa)	53
Conjugate	Unconjugate
Specificity	GSDMD (N-ternal) Rabbit Polyclonal Antibody detects endogenous levels of GSDMD protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Gasdermin D; Gasdermin domain containing 1; Gasdermin domain containing protein 1; GSDMD; GSDMDC-1; GSDMDC1
Gene Aliases	GSDMD
UniProt ID	P57764
Entrez Gene ID	79792

Product Description

GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

Product Image Gallery

Western blot analysis of extracts on different cells, using GSDMD (N-ternal) Rabbit Polyclonal Antibody (EAB10722) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Lane1: HepG2
Lane2: Mouse brain

Predicted band size: 53 kDa; Observed band size: 36,55 kDa

Immunohistochemical analysis of paraffin-embedded Human tonsil tissue, using GSDMD (N-ternal) Rabbit Polyclonal Antibody (EAB10722) at 1:200 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol