Monoclonal Antibodies - BNIP3L Mouse Monoclonal Antibody

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BNIP3L Mouse Monoclonal Antibody

Catalog #：EAB21911

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB21911-100UL	In Stock	100ul	$388.50

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
United States	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, IF/ICC, ELISA
Species Reactivity	Human
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:2000-10000 IF/ICC=1:200-1000
MW (kDa)	24
Conjugate	Unconjugate
Specificity	BNIP3L Mouse Monoclonal Antibody detects endogenous levels of BNIP3L protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	BNIP3A; BNIP3H; BNIP3L; C86132; D14Ertd719e
Gene Aliases	BNIP3L
UniProt ID	O60238
Entrez Gene ID	665

Product Description

Bnip3L, which is also designated Nip3L or Nix, is highly related to Nip3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins. The encoded protein binds to Bcl-2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release of cytochrome c. Nip3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL.

Product Image Gallery
Western blot analysis of extracts on different cells, using BNIP3L Mouse Monoclonal Antibody (EAB21911) at 1:5000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution. Lane1: Hela Lane2: K562 Lane3: Jurkat Predicted band size: 24 kDa; Observed band size: 35 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol