| SKU-Pack Size | Availability | Size | Price | |
| EAB21872-100UL | In Stock | 100ul | €297.70 |
| Please select the country you are in to find your local distributor. |
| Dianost | Phone£º+49 (0) 40 65472-053 | |
| Bullenkoppel 11£¬ 23896 Poggensee, | E-mail£ºola@olasciences.com | |
| Germany | Germany | Web£ºwww.olasciences.com |
| Product Information | |
| Applications | WB, IP, IF/ICC, FC |
| Species Reactivity | Human |
| Host / Isotype | Rabbit IgG |
| Clonality | Monoclonal |
| Applications Dilutions | WB=1:500-2000 IP=1:10-100 IF/ICC=1:50-200 FC=1:10-100 |
| MW (kDa) | 88 |
| Conjugate | Unconjugate |
| Specificity | BRAT1 Rabbit Monoclonal Antibody detects endogenous levels of BRAT1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
| Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
| Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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| Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
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| Product Bioinformatics | |
| Synonym(s) | BRCA1 associated ATM activator 1; BAAT1; RMFSL; NEDCAS; C7orf27; BRAT1 |
| Gene Aliases | BRAT1 |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. |
| Product Image Gallery | |
![]() Western blot analysis of extracts on Hela, K562 cells, using BRAT1 Rabbit Monoclonal Antibody (EAB21872) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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| Specific Protocols | |