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AtgL Rabbit Polyclonal Antibody
Catalog #£ºEAB11449
  SKU-Pack Size Availability Size Price
EAB11449-30UL In Stock 30ul €115.70
EAB11449-100UL In Stock 100ul €258.70
EAB11449-200UL In Stock 200ul €440.70
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Product Information
Applications WB
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit IgG
Clonality Polyclonal
Applications Dilutions WB=1:500-2000
MW (kDa) 55
Conjugate Unconjugate
Specificity AtgL Rabbit Polyclonal Antibody detects endogenous levels of AtgL protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) ATGL; FP17548; iPLA2zeta; PEDF-R; PNPLA2; RGD1309044; TTS-2.2; TTS2
Gene Aliases PNPLA2
UniProt ID

Q96AD5

Entrez Gene ID

57104

Product Description

The Adiponutrin family members, which have been implicated in obesity and diabetes, consist of Adiponutrin (ADPN), GS1, GS2, GS2-like, PNPLA1, and adipose triglyceride lipase (ATGL), also designated Desnutrin or Patatin-like phospholipase domain-containing protein 2 (PLNPA2). AGTL is a 486-amino acid protein that is highly expressed in mouse and human adipose tissue. It contains a highly conserved 180-amino acid N-terminal patatin domain common to plant acyl-hydrolases with a glycine-rich region, an aspartate active site motif, and an active serine hydrolase motif. Along with hormone-sensitive lipase, ATGL catabolizes stored triglycerides in mammalian adipose tissue. The lipase activity of AGTL is dependent upon the presence of an activated serine residue. ADPN and ATGL are oppositely regulated by insulin, where upregulation of ATGl and downregulation of ADPN occurs when fasting.

Product Image Gallery
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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