Recombinant Antibodies - HSP20 Rabbit Monoclonal Antibody

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HSP20 Rabbit Monoclonal Antibody

Catalog #：EAB21828

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB21828-100UL	In Stock	100ul	€297.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	Dianost	Phone：+49 (0) 40 65472-053
	Bullenkoppel 11， 23896 Poggensee,	E-mail：ola@olasciences.com
Germany	Germany	Web：www.olasciences.com

Product Information
Applications	WB, IHC-P, FC
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000 　 IHC-P=1:50-200 FC=1:10-100
MW (kDa)	17
Conjugate	Unconjugate
Specificity	HSP20 Rabbit Monoclonal Antibody detects endogenous levels of HSP20 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Heat shock protein family B (small) member 6; Heat Shock Protein 20; HEL55; Hsp20; PPP1R91; HSPB6
Gene Aliases	HSPB6
UniProt ID	O14558
Entrez Gene ID	126393

Product Description

HSP20(Heat Shock Protein 20) also known as HSPB6 is a ubiquitously expressed molecular chaperone, with higher levels found in skeletal, cardiac, and smooth muscle. HSP20 plays a cardioprotective role in response to injury through cardiac β-adrenergic signaling, which induces increased HSP20 protein expression and phosphorylation at Ser16 by PKA. Phosphorylation of HSP20 at Ser16 protects cells from undergoing apoptosis and mediates HSP20 interaction with the cytoskeleton. Constitutive phosphorylation of HSP20 at Ser16 in mice leads to fibrosis and heart failure through interleukin-6 (IL-6) and STAT3 signaling.

Product Image Gallery
Western blot analysis of extracts on Human skeletal muscle, Mouse skeletal muscle cells, using HSP20 Rabbit Monoclonal Antibody (EAB21828) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol