SKU-Pack Size | Availability | Size | Price | |
EAB21712-100UL | In Stock | 100ul | €297.70 | |
EAB21712-200UL | In Stock | 200ul | €479.70 |
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SBT BioChem Srl | Phone£º+39 05 7156 8147 |
Via Ponte di Bagnolo, 811 Bologna, | E-mail£ºinfo@sbtbiochem.it | |
Italy | Italy | Web£ºwww.sbtbiochem.it |
Product Information | |
Applications | WB |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit IgG |
Clonality | Monoclonal |
Applications Dilutions | WB=1:500-2000¡¡ |
MW (kDa) | 65 |
Conjugate | Unconjugate |
Specificity | NOX2/gp91phox Rabbit Monoclonal Antibody detects endogenous levels of NOX2/gp91phox protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | CGD; CGDX; NOX2; IMD34; AMCBX2; GP91-1; GP91PHOX; gp91-PHOX; GP91-PHO; NADPH oxidase 2; P91PHOX; p91-PHOX |
Gene Aliases | CYBB |
UniProt ID | |
Entrez Gene ID |
Product Description | |
Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. |
Product Image Gallery | |
![]() Western blot analysis of extracts on different cells, using NOX2/gp91phox Rabbit Monoclonal Antibody (EAB21712) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Lane1: MCF7 Lane2: THP-1 |
Specific Protocols | |